USP5 motivates immunosuppressive microenvironment in multiple myeloma by activating STAT2-PFKFB4-mediated glycolysis

Abstract Background Glycolysis, a classic characteristic of cancer cells, can drive cancer progression by generating lactate, which play as a key immunosuppressive mediator.Currently, ubiquitin-specific proteases 5 (USP5) has been demonstrated to facilitate tumor cell survival in multiple myeloma (MM), whereas whether USP5 was involved in glycolysi

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Body as a Medium and Metaphor in the Context of Performance Art

Consciously or unconsciously, a new subversive world has been built with the change of consciousness, cultural segments, environment and reality experiences, as well as the emerging denial of form and art as contemplative medium, and the demolition of standards by artists who dictated the aesthetics of beauty and exclusivity of thematic freedom.Dur

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